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doi: 10.1016/j.canlet.2018.06.016, 86

Oracea should not be used during pregnancy, by nursing mothers or by children under 8 years of age

A large clinical study in South Korea of 629 patients who underwent spinal fusion also found that post-operative patient satisfaction was around 71%, with unsatisfied patients reporting the persistence of chronic pain after the surgery (Kong et al., 2010)