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In the same vein, the Randomized European Celecoxib Trial, a phase 3, randomized, double-blind study (NCT02429427), did not show any evidence of DFS benefit in breast cancer patients [293]

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doi: 10.1111/j.1476-5381.2010.00905.x 86 MarkiewskiMMLambrisJD

Controlled studies found gray matter increases on MRI after an eight-week mindfulness program and after two months on a 3D video game, in the hippocampus among other regions, though these were short studies of volume rather than long-term cognition