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Side effects for both may include nausea, gastrointestinal discomfort, and potential changes in appetite

Do both require refrigerated storage

Menopause supplements are available over-the-counter and may support mild symptoms of menopause

It is also possible that generation of nicotinamide by CD38 may regulate SIRTUINs activity, since nicotinamide is an endogenous inhibitor of the SIRTUINs [62-63]