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193 A possible mechanism underlying the antibiotic-induced cholinergic dysfunction is the elevated activity of corticohippocampal acetylcholinesterase (AChE), which leads to increased acetylcholine breakdown

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Furthermore, using soybean for animal feed competes with its use as a protein source for humans

However, retention of significant in vivo activity beyond the point where most of the RWJ-58259 had been consumed implies the generation of an active metabolite