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[DOI] [PubMed] [Google Scholar] 50.Meister A., Anderson M.E

Despite being frequently prescribed, MTXs severe multiple toxicities can occasionally limit its therapeutic potential

Swapping between assessors or knowing the exposure group of the investigated offspring could inadvertently skew the data

Some people use it in higher doses, or in forms like capsules or sublingual tablets

Despite completing multiple phase III trials with positive data on testosterone and fertility endpoints, the branded formulation (Androxal) did not receive FDA approval, partly due to disagreements about the appropriate clinical indication and comparator design