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Abdominal irradiation induces intestinal epithelial cell apoptosis and that treatment with GH or IGF1 treatment can significantly inhibit this effect (Mylonas et al., 2000), while there is study also suggests that GH shows radioprotective effect through increasing local IGF1 level and counteracting cell apoptosis (Mahran et al., 2015)

Biotechnology Advances, 23 , 15501561

Briefly, brains of 3MST knockout mice or the wild-type mice were removed at the postnatal day 1 or 2 and submerged in the ice-cold Leiboritzs L-15 medium (Life Technologies, Waltham Massachusetts, USA)