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is a consultant to Merck, owns equity in Gilead and received payment from IQVIA and Curio Science

[9] Numeric pain scales like Patients Global Impression of Change scale and Likert-type pain intensity scale have shown remarkable improvement in pain symptoms due to methylcobalamin neuralgia.[10] It not only reduces the pain symptoms but also ensures improved quality of life.[11] Neuroprotection and Neuro-synthesis The majority of therapeutic activity of methylcobalamin is in the form of an analgesic and regulator of homocysteine is due to its positive role in promoting the action and structure of nerve cells as well as providing mechanisms for regeneration of damaged neurons.[12] Methylcobalamin functions to restore the integrity and strength of the myelin sheath resulting in increased neuroprotection and improved neural conductance

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We believe that an enhanced understanding of [] the structural changes within intervertebral disc tissue and inflammatory responses will help identify novel therapeutic targets and enable effective treatment. Within the spine there are numerous chemical messengers released by neurons called neurotransmitters that carry signals and information between cells

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