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Such cells have been described as coordinators of a protective immune response against Mtb through a Th1 response

Chen, C.-L., Lin, C.-F., Chiang, C.-W., Jan, M.-S

doi: 10.1371/journal.ppat.1011406 176 ChitimusDMet al

In addition, we found that the downregulation of ACs metabolism-related genes and protein expression by VPA in both mouse liver and hepatocytes was dose-dependent, i.e., the greater the VPA concentration, the more pronounced the downregulation effect

The mitogen-activated protein kinase (MAPK) family comprises three major subfamilies with distinct and sometimes opposing functions: extracellular signal-regulated kinase 1/2 (ERK1/2), c-Jun N-terminal kinase (JNK), and p38 MAPK