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Description

Here, we have reported the discovery of two allosteric ME2 inhibitors, EA and MDSA, that are capable of inhibiting ME2 activity and thus decreasing the production of cellular pyruvate, NADH, and ATP

Elution of anti-spectrin antibodies from red cells in homozygous b-thalassemia

Hyperhomocysteinemia was related to vitamin B12 or folate deficiency in 55%, mutations in one or more genes of one-carbon or vitamin B12 metabolism in 11%, and severe renal failure in 15%