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All these data thus point toward a mechanism of regulation of CBS expression at the transcriptional level involving the Nrf2 pathway

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Data availability Normalized RNA-seq data for the sets developed in this study has been publicly deposited at the R2 Genomic Analysis and Visualization Platform ( under the dataset names: NB_Aur-COJEC_PDX1_invivo (for in vivo data) and Neuroblastoma Auranofin Comb PDX1andPDX3R_org (for organoid data)

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The absorbance was measured at 450 nm using a microplate reader (Model 680