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These targeted delivery systems ensure high curcumin concentration directly at the diseased site for extended periods, which is ideal for chronic periodontitis management ( 4.6 Toothpastes and chewing gums Curcumin has been included in some herbal toothpastes aimed at reducing plaque and gingivitis

Moreover, many ADC programs still rely on single-threshold biomarker definitions (e.g., IHC 2 +/3 +) that fail to account for temporal and spatial variation in target expression, TME context, or drug penetration potential [259, 306, 307]

Similarly, in a study on E

Many patients use this time to relax, meditate or catch up on work

As a result of oxidation which is a natural process during the process of metabolism, the formation of free radicals, which cause various damages in the organism and initiator of some vital chronic diseases such as cancer and heart diseases, increased the interest in antioxidant compounds that combat them, and studies on this subject mostly focused on the determination of antioxidant activities