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Through oral administration, it also can inhibit the IL-12 and TNF- expression, as other flavones can interact in the NF-B pathway in UC attenuated [110]

They reported that the concentrations 416 mg/kg have a promising antiepileptic potential and protected the mice against myoclonic jerk and generalized tonic-clonic jerk compared to the sodium valproate

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It has been shown that genistein can inhibit the NLRP3 inflammasome via TGR5-cAMP signaling in human macrophages (105)

Also, there are differences in SASP expression profiles and functions between senescence-inducing conditions and cell types [54]