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Moreover, FSP1, which locates in the plasma membrane, prevents lipid peroxidation and inhibits ferroptosis even in the absence of GPX4 [56]

a study in rats of a single-tablet combination demonstrated that including methionine could minimize liver toxicity (measured by serum ALT and AST) at therapeutic (100 mg/kg) and highly toxic (1000 mg/kg) acetaminophen doses (Iyanda 2010)