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Altered regulation of iron metabolism has been shown to play a role in the pathogenesis of HCC, particularly in patients who present with NASH, hemochromatosis, or thalassemia [91, 92]

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Further results showed that bupivacaine decreased mitochondrial membrane potential, decreased GSH, increased MDA levels, and attenuated the phosphorylation of PI3K, Akt, and mTOR ( Levobupivacaine (L-bupivacaine), a new long-acting amide local anaesthetic, is an isomer of bupivacaine and has potential antitumour properties

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At 5 years and 9 months of age, the EEG during stage II of sleep showed 12 Hz high-amplitude dysrhythmic slow-wave activity with rare multifocal spikes or sharp waves in the and background activity, which is suggestive of modified hyporegulation