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It influences satellite cell activation and promotes intracellular pathways associated with protein synthesis and tissue regeneration

10.1111/j.1476-5381.1972.tb07257.x 28 Brigelius-FlohR.MaiorinoM

In a rat model of HFD-induced MASLD, serum levels of IL-22 were markedly reduced, while the hepatic expression of the autophagy marker LC3B was increased

3.3 Insulin-like growth factor binding protein 3(IGFBP-3) IGFBP-3 is the most abundant member of the IGFBP family, primarily functioning to regulate IGF bioavailability through direct binding while also modulating cell proliferation and apoptosis via IGF-independent mechanisms

It shows promise in addressing neurological decline linked to conditions like Alzheimers and has the ability to reset pathological gene expression