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Celecoxib treatment resulted in a 45% reduction in mammary PGE2 levels and attenuated mast cell influx and angiogenesis, suggesting that COX-2-selective inhibitors may be useful in the prevention or treatment of breast cancer associated with elevated human IGF-1 levels (110)

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Reduce Stress Chronic stress is one of the main root causes of inflammation, pain, and disease

Additionally, iron overload can activate inflammatory responses, initiating cell death pathways such as apoptosis and autophagy (101, 102), further accelerating myocardial cell damage and death