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To generate mito GCL (E103A), the forward and reverse oligonucleotides 5-CAGAGTATGGGAGTTACATGATT GCA GGGACACCTGGCCAGCCGTACGGA-3 (mutant nucleotides underlined) were used

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Table 1 Environmental factors that increase risk for systemic autoimmune rheumatic diseases

More severe neurological manifestations resulting from cortical atrophy, hydrocephalus, necrosis, and demyelination have been noted in some patients [3]