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The combination is well-tolerated because cagrilintide targets amylin receptors while semaglutide activates GLP-1 receptors, meaning the mechanisms dont overlap and produce additive effects rather than redundant signalling

5 Preclinical screening of luteolin in pulmonary diseases 5.1 In vitro studies In chronic pulmonary diseases like COPD and PF, oxidative stress and inflammation are major pathological drivers