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Furthermore, there is some evidence from a rodent model that translocator protein radioligand uptake may be influenced by exercise (67), which is another argument for the importance of including sedentary controls in studies of ME/CFS

The immunosuppressive properties of the tumor microenvironment (TME) further limit its efficacy: regulatory T cells (Tregs) suppress ferroptosis by consuming cysteine and secreting IL-10, while tumor cells escape through the Nrf2 pathway by upregulating GPX4 and FSP1