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## **Billing requirements** When billing HCPCS code J3420 (Vitamin B12 injection), healthcare professionals must document medical necessity in the patients medical record

Methylcobalamin begins degrading within 23 hours at ambient temperature, and lipotropic amino acids follow within 68 hours

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However, they do occur in a segment of the population

Non-Squamous NSCLC First-line Treatment of Metastatic Non-squamous NSCLC with Pembrolizumab and Platinum Chemotherapy The safety of pemetrexed for injection, in combination with pembrolizumab and investigator's choice of platinum (either carboplatin or cisplatin), was investigated in Study KEYNOTE-189, a multicenter, double-blind, randomized (2:1), active-controlled trial in patients with previously untreated, metastatic non-squamous NSCLC with no EGFR or ALK genomic tumor aberrations