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Treatment with NAC substantially reduced liver toxicity when given one or two hours after the overdose

In pancreatic cancer, knocking out the ACOT8 gene promotes ferroptosis and increases the tumor's chemosensitivity to gemcitabine [118]

however, the limited number of RCTs precludes definitive conclusions on the efficacy or safety of microbiome-based therapies, necessitating more RCTs for validation