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An alternative approach is the de novo synthesis of compounds, which offers several advantages, including rapid proliferation, year-round metabolite production independent of environmental conditions, and sometimes the metabolite content is higher compared to the mother plant 5,6

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Mehta A, Sigman M

(2) treatment with buthionine sulphoximine (BSO, 1000 M) to block de novo GSH synthesis for 2448 h

Energy Expenditure and Metabolic Rate Beyond appetite suppression, tesofensine demonstrates effects on energy expenditure and metabolic rate that contribute to its anti-obesity properties