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doi: 10.3390/ijms25021344 67 AitkenRJ

Hepatocytes were transfected with 2.75 M dsiRNA (Integrated DNA Technologies, Coralville, IA) in nuclease-free duplex buffer using the Viromer Blue transfection kit (Origene) following the manufacturers protocol

Ez a szintetikus izomer nemcsak inaktv, hanem kompetitv mdon gtolja az L-karnitin transzportmechanizmusait a szervezetben, amivel mestersgesen elidzett karnitinhinyt s az ezzel jr izomgyengesget vagy akr szvizom-krosodst okozhat