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With this addition, glutathiones role in mitigating toxicity from quinone-derivatives is combined with its overall kinetics providing a link between glutathione depletion in different compartments with quinone redox

Of course, inadequate dietary intake can cause B12 deficiency, which is why vegans and vegetarians have such high levels of B12 deficiency

50 FXR, in addition to having an essential role in carbohydrate and lipid metabolism, exerts effects on some genes that regulate enzymes in the urea cycle and acts as a transcriptional regulator of ammonia detoxification via ureagenesis and glutamine synthesis in the liver

(1997a) described a possible somatic mutation in the von Hippel-Lindau ( VHL ) tumor suppressor gene in the etiology of renal cell carcinoma arising from exposure to trichloroethylene

Neurochem Int 46(8):601611