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Regulatory bodies such as the FDA and EMA have implemented rigorous guidelines to address the specific challenges encountered with pulmonary nanotherapeutics, ensuring comprehensive preclinical evaluations including pharmacokinetics, biodistribution, and toxicity studies, with particular attention to lung-specific endpoints like alveolar inflammation and mucociliary clearance ( 2+ release (Sun et al., 2023)

Protocols are based on early research in small cohorts

Lack of association between serum vitamin B, vitamin B(12), and vitamin D levels with different types of Glaucoma: a systematic review and Meta-analysis

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