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A review: exploring synthetic schemes and structure-activity relationship (SAR) studies of mono-carbonyl curcumin analogues for cytotoxicity inhibitory anticancer activity

The one everyone quotes is molecular weight: Under ~500 Da is the rough cutoff for good passive oral absorption

doi: 10.1038/s41398-018-0353-x 21 CaoB.WangD.PanZ.McIntyreR

For individuals, both adults and children, with moderate-to-severe AD, long-term use of medium-potency TCs in combination with proactive twice-weekly treatment using emollients can help minimize the risk of relapse [26]