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Because retatrutide includes GLP-1 agonism (which semaglutide was providing) plus GIP and glucagon agonism, the transition should not result in loss of appetite suppression during the switch

The primary contraindication is a personal history of cancer, since its growth hormone-stimulating mechanism is not appropriate for patients with any oncological history

Whether you explore hormones, peptides, or a combination of the two, make sure you go about it the right way

Business meals are the shit you eat when you need your body to be fueled appropriately for health, longevity, performance at work, body composition, and all that other stuff

It has been argued, in the broad context of synaptic plasticity at excitatory synapses, that an emphasis on [Ca 2+ ] i rise as the triggering mechanism of plasticity can offer improved explanatory value over a fixation on learning rules, such as STDP (Lisman and Spruston, 2+ ] i rise is strong local activation and local spread to inactive synapses or more global influx through voltage gated channels activated by back-propogating action potentials and amplified by release from internal stores