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Beyond the binary exposure definition, we observed exposure-intensity patterns

Yu YQ, Gamez-Belmonte R, Patankar JV, Liebing E, Becker C

Fibrosis and the bladder, implications for function ICI-RS 2017

Consistent with this, use of a reducing source such as -mercaptoethanol allows reversal of xCT-KO phenotype, as it has been reported couple decades ago by Bannai's group ( in vivo can explain the discrepancy with in vitro phenotype