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Again, you should undergo a comprehensive medical assessment to rule out, as much as possible, your likelihood of experiencing this potentially life-threatening complication

9 These studies provide a pathophysiological correlation for the four clinical phases of a migraine attack, which are prodrome, migraine aura, headache and postdrome (Figure 1)

Nature, 395 (6697), 89

The authors note the relevance of this study: "Compared to other studies, the patients in our study had relatively good glycemic control at the beginning of the trial and maintained good control during the entire follow-up period, whereas in most other studies glycemic control was poor at the baseline and improved to suboptimal level during the course of the study

Such rapid dynamics allows timely adaptive response to episodes of short-term hypoxia, which is especially important in the case of periodic hypoxia, and HIF-1, apparently, is a critical factor in initiating and reversing adaptive reactions to periodic hypoxia