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The findings indicated that FGF-2 enhances radiographic bone filling, particularly when combined with bone substitutes, although it did not yield additional benefits regarding secondary probing pocket depth or probing attachment levels [106]

Without a preservative, though, it offers no protection against microbial growth once the vial has been accessed, which is why solutions reconstituted with sterile water carry a meaningfully shorter usable window than those prepared with bacteriostatic water