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Rx Only Takeda PRINCIPAL DISPLAY PANEL - Kit Carton - 1000 IU ADYNOVATE [Antihemophilic Factor (Recombinant), PEGylated] NDC 0944-4624-01 Single-dose only For Intravenous Administration After Reconstitution Only Lyophilized powder for reconstitution ADYNOVATE and diluent preassembled in BAXJECT III system Rx Only Actual potency Takeda PRINCIPAL DISPLAY PANEL - Barrel Label - 1000 IU ADYNOVATE [Antihemophilic Factor (Recombinant), PEGylated] For Intravenous Administration Only ADYNOVATE and diluent preassembled in BAXJECT III system Directions for use: see package insert Rx Only IU: LOT: EXP: Takeda 6521224 PRINCIPAL DISPLAY PANEL - Blister Label - 1000 IU ADYNOVATE [Antihemophilic Factor (Recombinant), PEGylated] NDC 0944-4624-02 Single-dose only 6521493 For Intravenous Administration Only ADYNOVATE and diluent preassembled in BAXJECT III system Do not open until time of use Do not use if packaging is opened or damaged Discard unused portion

Therefore, the use of ferroptosis induced by these therapies could further increase the effectiveness of cancer treatment

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0.5%, respectively (Group1 vs Group 2: p=0.07, Group 2 vs Group 3: p=0.1, Group1 vs Group3: p 30IU/L or HBV-DNA 3.3logIU/ml, and Group3 (126 cases): NA group