B12 Side Effects in Elderly: Safety Guide for Older Adults Vitamin B12 supplementation is commonly prescribed for elderly patients, as deficiency becomes increasingly prevalent with age due to reduced gastric acid production, pernicious anaemia, and medication interactions

Disclosure of interest: Jessica Seetge: nothing to disclose, Balzs Cske: nothing to disclose, Zsfia Nozomi Kardi: nothing to disclose, Edit Bosnyk: nothing to disclose, Lszl Szapry: nothing to disclose E-Posters - RECOVERY, REHABILITATION AND OUTCOME 03.00 - RECOVERY, REHABILITATION AND OUTCOME - 03.02 - LIFE AFTER STROKE P2180 - ESOC25-73 FACTORS ASSOCIATED WITH POST-STROKE MOOD DIFFICULTIES ASSESSED USING THE STROKE IMPACT SCALE-64 IN MULTI-ETHNIC POPULATION Min Sun Kim 1 , L Brian Hickman 2 , Katherine Mun 2 , Nerses Sanossian 3 , Sidney Starkman 2 , Gilda Avila-Rinek 2 , Latisha Sharma 2 , David Liebeskind 2 , Robin Conwit 4 , Scott Hamilton 5 , Jeffrey Saver 1 Brigham and Women's Hospital, Boston, United States, 2 UCLA Medical Center, Los Angeles, United States, 3 USC Medical Center, Los Angeles, United States, 4 National Institute for Neurological Disorders and Stroke, Bethesda, United States, 5 Stanford University, Palo Alto, United States Background and Aims: Studies on predictors of post-stroke mood difficulties have shown inconsistent results, in part due to limitations in mood/depression scales in stroke patients

For all B12 biomarkers, information should be collected on age, gender, ethnicity, pregnancy, folate status, and presence of possible bacterial overgrowth because all these factors impact B12 biomarkers
B12 (when taken with dexamethasone, an anti-inflammatory steroid medication) has also been shown to increase the activity of nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF), which promote nerve survival and regeneration
Polymers, 14(4), 724