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Am J Physiol Heart C 2007;293:H48H59

Since the development of neuropathic pain can be related to a previous peripheral nerve injury [15], the aim of this narrative review is to provide a comprehensive update of the literature in order to improve the knowledge about the potential beneficial effects of polyphenols on peripheral nerve regeneration

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Increased tryptophan metabolism can lead to a shift toward the KYN pathway (24)

Its anti-inflammatory supportive properties are particularly noteworthy in the context of chronic inflammatory conditions, such as inflammatory bowel disease (IBD), arthritis, and various skin disorders