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doi:10.5326/JAAHA-MS-5825

Thiamine, a heterocyclic water-soluble compound

Dosage and frequency are determined by a healthcare provider based on the individual's needs

Key Takeaways MOTS-c activates AMPK to shift cellular metabolism toward fat oxidation and improve insulin sensitivity, while 5-Amino-1MQ inhibits NNMT to preserve NAD+ required for mitochondrial function

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