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In a mouse tumor model, oral green tea increased doxorubicin concentration in the tumor and enhanced doxorubicins inhibition of tumor growth 2.5-fold (Sadzuka 1998)

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Discontinuation There is no documented discontinuation syndrome and no need to taper off

Treatment with ACEIs or ARBs reduces EGR1 expression in glomeruli, inhibits renin expression, decreases secretion of TNF-a and fibronectin proteins (FN) from tethered cells, slows tethered cell injury, and affects the behavior of MCs [75]