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Thus, we hypothesize that long-term use of Naltrexone may benefit patients with combined metabolic and alcohol-associated liver disease (MetALD) with lower rates of decompensated liver disease

Other treatments, such as vitamin C or K, do not have strong research behind them, and some methods have risks

Ferritin plays many roles in sensing and regulating cellular iron levels ( Fth1 knockout caused a reduction in renal fibrosis compared to the wild-type control (Supplementary Figure S2B)

Look for reduced glutathione (GSH), not oxidized (GSSG)

Nevertheless, the interactions between different mitophagy-mediated pathways and the exact mechanisms by which mitophagy influences disease initiation and progression are still unclear and require further exploration