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Indeed, VPA has fewer common side effects than do other AEDs, especially on behaviour and cognitive functions

Compared with NNT wild-type mice (C57BL/6N mice), isolated liver mitochondria from C57BL/6J mice had higher NADH/total NAD(H) and lower NADPH/total NADP(H) on ADP stimulation, which correlated with a reduced rate of removal of exogenous organic peroxides (33, 81)