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Studies have found that in ovarian cancer tissue samples, there are a group of cell subsets similar to embryonic stem cells, which express high levels of CD44, CD133, c-Kit (CD117), and other markers, displaying "stemness" similar to stem cells, but with the characteristics of tumor cells

doi: 10.1038/s41467-021-20893-2 161 WenJWangSGuoRLiuD

Although similarity-based screening methods are reliable, they may miss lead compounds with entirely new mechanisms of action

It is believed that instead of involved in ATP synthesis primarily, neutrophil mitochondria appear to have diverse functions including mtDNA copy number and mitochondrial potential [141]

doi:10.1016/j.bbagen.2012.09.018