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~50% patients develop end-stage renal disease in 10-15 years

Notably, AD patients exhibit heightened SOD activity, diminished glutamine synthetase activity, and elevated lipid peroxidation, collectively resulting in heightened oxidative stress and accumulation of free radicals

Most protocols begin at 0.51 mg weekly or 2 mg monthly

Pediatr Res (2004) 56(2):21926

Acute Lung Injury Protection Acute lung injury protection in LPS-induced mouse models shows: Pulmonary fibrosis studies using bleomycin-induced injury demonstrate reduced inflammatory cell infiltration, reduced interstitial thickness, and reduced TNF- and IL-6 expression at doses of 2.6-260 g/mL/day