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Table 2, both extract and compound inhibited the enzyme at low potency, exhibiting IC 50 values 26 and 143 times higher than the control, respectively

The right choice depends on whether the injury is discrete and localized or diffuse and multi-site

& Matthews, D

This involvement of RIP3 in APAP-induced acute liver injury is supported by several reports showing upregulation of RIP3 protein expression in ethanol-induced liver injury