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this reaction is reversible and is affected by pH [287289]

CagA interacts with LRP8 to form the CagA/LRP8/-catenin complex, which further amplifies H

In contrast, limited fatty acid availability leads to reduced ROS production and increased autophagy, due to the anti-inflammatory effect of AMP-activated protein kinase, thereby inhibiting other forms of cell death and the inflammatory response (181)

Nevertheless, the prognosis of PDAC patients remains suboptimal owing to resistance to GEM chemotherapy [22]