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Pharmacological inhibition of JNK prevented 4-HNE-induced LC3-II formation, suggesting that 4-HNE triggered autophagic responses could be partly attributed to ER stress [155]

R.LehmanC

10.1091/mbc.E12-06-0447 Mol

NRF2 then dimerizes with members of the sMaf proteins through its bZIP domains and binds to the ARE sequences, which are regulatory enhancers, within gene promoters [156, 161]