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Cristian Scatena, University of Pisa, Italy Updates Copyright 2021 Ajaz, Zaidi, Ali, Siddiqa, Memon, Firasat, Abid and Khaliq

This remodeling is consistent with a shift in the fissionfusion balance toward excessive fission and/or compromised fusion dynamics under cisplatin-induced stress

Many nuclear receptors retain full ligand-dependent transcriptional activity by binding to coactivators containing short leucine-rich LxxLL motifs (where x can be any amino acid) known as nuclear receptor (NR) boxes 78

Chronic epigenetic effects like histone and DNA methylations are quite stable and may be inherited as a memory by offspring cells [196]