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In addition, swimming speed or immobility are often used as control variables

These may correspond to the intracranial (superior sagittal sinus), portal, and caval hypertension, aortal hypotension, ECG disturbances, brain swelling and lesions, heart dysfunction, lung lesions, liver, and kidney failure, gastrointestinal lesions, widespread arterial and venous thrombosis, venous congestion (i.e., inferior caval vein and superior mesenteric vein), and venous failure (azygos vein) in the occlusion/occlusion-like syndromes [18,19,20,21,22,23,24,25,26,27,28,29,30]

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The review also described TB4s ability to decrease the number of myofibroblasts in wounds, resulting in decreased scar formation and fibrosis