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There's been an uptick in interest because it's been all over Instagram and the media, says Amanceias founder Ann Czarnik, who also works as an emergency medicine physician

Melinda Ring, director of the Osher Center for Integrative Health at Northwestern University Feinberg School of Medicine, said the body naturally produces thousands of peptides, regulating "everything from hormone signaling to immune response and tissue repair." "And it does so through tightly controlled feedback mechanisms, in precise amounts," she explained

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Signs include fatigue, weakness, and balance problems