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Similarly, in primary neurons, we also found that knockdown of A-SYN by siRNA lentivirus mitigated hypoxia-induced neuronal death (Supplemental Fig

The strong reduction of Iba1 is particularly noteworthy because human and animal studies have shown that microglia can be chronically activated for weeks to years after brain trauma (Gentleman et al, 2004

That figure came from an assay-specific in-vitro spine-density assay (picomolar Dihexa versus nanomolar BDNF) and does not mean Dihexa is millions of times more effective in a living brain

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