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Astrocytic pathology in Alpers syndrome

The mainstream copper-biology research community and the broader peptide research community have engaged with the GHK-Cu literature at various points, but the depth of independent characterization outside the Pickart-affiliated research has been variable

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In mice, knockout of a single H1 subtype does not cause a pronounced phenotype or significantly affect development, which only becomes compromised when multiple isoforms are inactivated 53,54,55,56