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The preliminary results presented in this study demonstrate the potential of the cannabis-responsive biomarker database in conjunction with ML applications to provide insight into the pharmacokinetics, pharmacodynamics and MOA of cannabinoids and on targets in endocannabinoid system (ECS)-related disorders, and to identify new Cannabis phytoconstituents with potential therapeutic roles

For instance, -caryophyllene is a selective CB2 agonist with known hepatoprotective effects, which could complement the reduction in CB1 receptor expression observed in our study (Gertsch et al