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Niacinamide also rarely causes adverse reactions

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Observation of the test subjects occurred until their natural deaths in order to calculate mean and maximum lifespans, as well as the age corresponding to 90% mortality rate [3]

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Notably, while our results confirm the suppression of core apoptotic signals, the specific contributions of the intrinsic and extrinsic apoptotic pathways and the potential involvement of GSDME-mediated pyroptosis in our model remain to be fully elucidated