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Deferasirox alleviates DSS-induced ulcerative colitis in mice by inhibiting ferroptosis and improving intestinal microbiota

Alternatively, a large body of animal and clinical data demonstrate that severe depletion of intracellular GSH is detrimental 28,29 , suggesting that pharmacological application of ROS or temporary disruption of endogenous GSH synthesis, for the purpose of depleting GSH, is hazardous